Principal Scientist, Analytical R&D

Company: HCPro, Inc.
Location: Boulder
Posted on: September 12, 2020

Job Description:

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

We are seeking an analytical chemist for our Boulder, CO site. This individual will work with the current analytical staff and partner with the process chemistry and formulation teams being established to advance the robust Boulder portfolio. The Pharmaceutical Sciences laboratory in Boulder was established to provide local support to the Boulder Medicinal Chemistry group, focusing on early process chemistry and formulation support for the pre-clinical and early development portfolio.

The candidate would be responsible for continuing to establish the analytical support of a Pharmaceutical Sciences laboratory at the Boulder site. The role requires direct lab work and the development of analytical strategies to enable successful pre-clinical formulations bulk deliveries and bulk deliveries for clinical and toxicology studies. Excellent communication skills are required to ensure connectivity with both the Boulder Pharmaceutical Sciences lab, local Medicinal Chemistry colleagues and the broader Analytical Research and Development Group. Additionally, the candidate needs to have a demonstrated ability to work on multi-disciplinary teams.

How You Will Achieve It

Establishing an Analytical Research and Development (ARD) laboratory at the Boulder site with state-of-the-art equipment (e.g. UHPLC-MS, GC-MS, XRF)

Individual lab work focused on early development oncology candidates with a focus on developing the analytical methods and strategies to support the enabling and development of scalable processes and pre-clinical formulations.

Mentoring of peers and establishment analytical workflows and development strategies.

Interaction with analytical colleagues within Boulder Medicinal Chemistry to advance the oncology portfolio and new technology across sites and lines.

Direct interaction and effective collaboration with project team members, including presenting data at project team meetings; critical review of data; and active involvement in solving technical challenges that arise during development

Strong oral and written communication skills including other global Analytical Research and Development colleagues as well as interactions with Boulder colleagues, in particular process chemistry, formulations development, and Boulder Medicinal Chemistry

Excellent written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise written reports, publications and related documents.

Compliance on safety and regulatory requirements.

Travel may be required in support of manufacture (Groton KL) and to engage with the broader ARD team, and to participate in scientific conferences.

Qualifications

Must-Have

B.S., M.S. or Ph.D. (Analytical Chemistry or related field) + relevant experience that includes: 15 years (B.S), 10 years (M.S), or 5 years (Ph.D) of relevant industrial experience in an Analytical Pharmaceutical Sciences/CMC lab environment.

Demonstrated experience with chromatographic method development and ability to run, interpret, and troubleshoot a wide variety of analytical instrumentation (e.g. UHPLC-MS, GC-MS, NMR, etc.)

Ability to meet project milestones with minimal supervision, to interact with multi-disciplinary teams, and to manage expectations for specific projects.

Demonstrated experience with both analytical laboratory data as well as process relevant data are a requirement to be successful in this position

Experience in problem-solving skills and delivery of technology/transfer/submission-ready technology, data and documents

Demonstrated oral and written communication skills, especially adherence to laboratory notebook practices and colleague mentoring.

Experience with instrument troubleshooting and a wide-variety of software and information systems (e.g. electronic lab notebooks, Empower and LIMS)

Ability to work in a team environment in a laboratory environment performing experiments.

Ability to perform data analysis, record results in electronic lab notebooks and effectively communicate in a team environment.

Ability to adhere to safe laboratory practices.

Other Job Details:

Eligible for Relocation Package: YES

Eligible for Employee Referral Bonus: YES

#LI-PFE

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

Keywords: HCPro, Inc., Boulder , Principal Scientist, Analytical R&D, Other , Boulder, Colorado