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Senior Research Associate, Chemistry - 2172

Company: Editas Medicine
Location: Boulder
Posted on: November 16, 2021

Job Description:

What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We're focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We're looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

Key Responsibilities & Accountabilities:

  • Perform automated synthesis of oligonucleotides on a variety of scales and instruments including Bioautomation Mermade 12 and GE Healthcare Akta 100 synthesizers.
  • Perform process development, scale up and process optimization.
  • Conduct cleavage, deprotection and other upstream post-synthesis work-up procedures.
  • Perform various analytical techniques to ensure final product meets specifications including LCMS, UPLC and UV spectroscopy.
  • Perform instrument and equipment preventative maintenance and repairs.
  • Maintain an electronic laboratory notebook and miscellaneous documentation.
  • Maintain reagent inventory.

    Requirements

    Knowledge, Skills & Capabilities:
    • Experience in solid phase synthesis, cleavage and deprotection of oligonucleotides.
    • Experience with laboratory automation.
    • Excellent oral and written communication skills.
    • Proficient with Microsoft Office programs.
    • Technical troubleshooting and organizational skills.
    • Ability to work effectively in a cross-functional team environment.
    • Excellent time management.
      Education & Relevant Work Experience:
      • Requires a Master's Degree or equivalency in Chemistry or related Life Science Degree with a minimum three years of relevant experience or a Bachelor's Degree or equivalency in Chemistry or related Life Science Degree with a minimum five years of relevant experience.

Keywords: Editas Medicine, Boulder , Senior Research Associate, Chemistry - 2172, Other , Boulder, Colorado

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