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Scientist II, Protein Therapeutics

Company: Mosaic Biosciences
Location: Boulder
Posted on: November 16, 2022

Job Description:

Mosaic Biosciences is seeking a Scientist II or Senior Scientist, Protein Therapeutics
We are growing our team and have an opportunity available for a full-time scientist to work within Mosaic's protein discovery and optimization team in our Boulder, Colorado laboratory. The successful candidate will work within a cross-functional team to drive protein and antibody therapeutics from discovery to preclinical development. The ideal candidate will have expertise in the discovery and development of protein therapeutics and have worked in the biopharmaceutical industry for more than 3 years.

  • Design and engineer novel recombinant proteins and next-generation antibodies.
  • Troubleshoot and optimize complicated isolation schemes to purify and refold recombinant proteins.
  • Bioconjugation and PEGylation of proteins.
  • Biochemical and biophysical characterization of proteins and antibodies.
  • Design and execute developability studies.
  • Participate in project teams to develop novel protein therapeutics.
    • Ph.D. or equivalent in molecular biology, biochemistry, or related field with 3+ years of biotech industry experience is required.
    • Thorough understanding of protein biochemistry and therapeutic discovery and development is required.
    • Experience with protein expression, purification, and characterization is required.
    • Experience with protein and antibody developability studies is highly desirable.
    • Experience with protein quality control and documentation is highly desirable.
    • Ability to identify creative solutions to challenging problems.
    • Effective time and resource management skills and an enthusiasm for working in a team environment.
      This is a full-time position in Boulder, CO with in-person work in our labs.Compensation Range: $90,000 - $120,000
      As a member of our team, you will be eligible for comprehensive, competitive, flexible benefits that include health and dental insurance, disability and life insurance, 401k with company match, and bonus opportunities based on company success.
      If you want to join us in discovering life-saving protein and antibody therapeutics, please apply via LinkedIn and/or by submitting your c.v. and a cover letter (strongly encouraged) via email to: Please reference the job title in the email subject line.
      About MosaicMosaic Biosciences, Inc. is a discovery and preclinical development company that partners with biopharmaceutical companies to discover novel protein and antibody therapeutics. Our experienced and dedicated research teams collaborate with our partners to design, manage, and execute research programs to rapidly advance programs, starting at any point from early discovery into preclinical development.
      Mosaic teams provide comprehensive, end-to-end discovery services, including: program assessment and strategy development; program management; antibody discovery and optimization; protein production, purification, and characterization; protein engineering; biochemical and cellular assay development; formulation, stability and developability studies; bioanalytical (PK and PD) assay development; and candidate-validating pharmacology.
      Based in Boulder, Colorado, we are a collaborative and talented team of scientists and entrepreneurs looking for dynamic, hardworking, creative thinkers who excel in a cutting-edge, science-driven, team environment.
      At Mosaic, we believe in a diverse workplace that celebrates all backgrounds and promotes individuality. We are committed to creating an inclusive environment with the purpose of furthering scientific innovation and supporting our employees by offering equal opportunities for all.

Keywords: Mosaic Biosciences, Boulder , Scientist II, Protein Therapeutics, Other , Boulder, Colorado

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